Long-term potentiation and depression of NMDA receptor-mediated synaptic transmission (NMDAR LTP/LTD) can significantly impact synapse function and information transfer in several brain areas.However, the mechanisms that determine the direction of NMDAR plasticity are poorly understood.Here, using physiologically relevant patterns of presynaptic an
Roger Ebert famously referred to movies as “machines that generate empathy”, arguing that cinema had the power to transport viewers into the lived realities and emotional experiences of people all across the world who are “sharing Canopy Hood this journey with us”.This is not an uncommon way of tackling the question of what film is good for
This article carries out a multifaceted legal analysis of the so-called Barroso Initiative, which was commenced by the European Commission in September 2006 in order to involve national parliaments of the Member States in the process of EU policy making.The key motive underlying the Initiative is to enhance the parliamentary and democratic dimensio
RlmN, a bacterial radical SAM methylating enzyme, has the unusual ability to modify two distinct types of RNA: 23S rRNA and tRNA.In rRNA, RlmN installs a methyl group at the C2 position of USB A2503 of 23S rRNA, while in tRNA the modification occurs at nucleotide A37, immediately adjacent to the anticodon triplet.Intriguingly, only a subset of tRNA
Perennial wildflower meadows contribute to the enhancement of the quality of urban green spaces, of-fering benefits for both people and wildlife.Significant impact is attributed to management in fostering species-diverse plant communities.However, there are not enough studies exploring the influence of early maintenance regimes on plant diversity.A